Our Mission

Fund Promising Research

Support scientifically sound studies that address important questions about ALS and build evidence for future progress.

Improve Diagnosis

Advance research on biomarkers and diagnostic tools to help identify ALS earlier and better understand its progression.

Advance Potential Treatments

Help promising discoveries progress through careful testing toward safe and effective therapies for people living with ALS.

Keep Patients at the Center

Support research guided by the needs of patients and families, with a focus on meaningful improvements in their lives.

Honor James’s Legacyts at the Center

Carry forward James Calcagnini’s generosity and hope for others through responsible stewardship of every contribution.

Open Science

Rigorous Research

Patient Benefit